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In addition, regulators and technology assessors have focused their interest on the ability of the translated measures to express and investigate equivalent concepts across languages, as most PRO measures for global use are developed in one language and subsequently translated for use in other countries and cultures (i.e., sequential approach) [6].
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This approach relies on the ability of the translating ribosome to protect a footprint of ~28 nt from RNase digestion (see Additional file 2: Figure S1).
Having small sample sizes to date from most U.S. ethnic groups has limited the ability to conduct validity studies of the translated measures.
We internally validated the predictive ability of functions translating scores into individual probability of nasal carriage of MRSA and the PPV of the rapid diagnostic test on a separate cohort from the same hospital (IVC).
Both the ability of REMO to reproduce the observed precipitation pattern and the ability of the HD Model to translate the grid cell based runoff provided by REMO into streamflow are assessed.
The mismatch is the outcome of different heat transfer coefficients across the crystallic structure of the nanoparticle and the fluid as well as the ability of the nanoparticle to translate and rotate, which as a result, gives rise to a different collective atomic activity (local temperature) between certain regions of the particle and the surrounding fluid atoms (this is confirmed in Fig. 6).
A final example demonstrates the ability of the system to translate results identified by microarray technologies, or other related high throughput technologies, to identify likely Xenopus homologues.
DOI: http://dx.doi.org/10.7554/eLife.05534.006 As we explored the kinetics of lysine incorporation, we evaluated the ability of the ribosome to translate a variety of MK(A or G 2 di-lysine messages.
The primary attenuating factor common to all three Sabin vaccines is a mutation located in the virus's internal ribosome entry site (IRES) which alters stem-loop structures, and reduces the ability of poliovirus to translate its RNA template within the host cell.
To evaluate whether the altered length of the 5'-leader sequences has any effect on the ability of the mRNA to be translated we tested reporter gene expression from constructs that had either the short or the long 5'-leader sequence (Fig. 5).
For his research on improving the ability of computers to translate one language to another, Hayden C. Metsky, 17, of Millburn High School in Millburn, N.J., won $10,000.
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CEO of Professional Science Editing for Scientists @ prosciediting.com