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To demonstrate the ability of the screen to identify beads bound to single molecules of hydrogenase DNA, we performed a test enrichment experiment.
wit was of particular interest because it has been previously implicated in NMJ function [27], [28] and thus could serve as a paradigm for validating the ability of the screen to identify bona fide Smn genetic modifiers.
Second, we estimated the ability of the screen to detect any given percent increase in lifespan.
To gain confidence on the ability of the screen to identify genuine SUMO substrates, we needed to confirm that our confident set contains bona fide SUMOylated targets.
Some of the novel mutants discovered in our screen have since been found in patients (5- 7), demonstrating the ability of the screen to anticipate clinically problematic drug resistance.
Receiver operator curve analysis using CTR01 data confirmed the ability of the screen to distinguish between the growth-inhibitory effects of shGFP and the neutral effects of cntrl-shRNAs.
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The first process demonstrates the ability of the screening models to identify favorable processing structures and illustrates the need to consider a rich enough set of processing configurations when generating the process superstructure.
The application of the screening models to an industrial siloxane monomer process demonstrates the ability of the screening models to identify favorable processing structures early in the design of a real-world example process, and illustrates how the screening models facilitate the dynamic optimization of particular process structures.
Discriminant analysis for classification of tissues types [ 9] was performed to determine the discriminative ability of the screened miRNAs.
Such methods are useful for detecting ALN metastasis, but may strongly depend on the personal ability of the screener.
Sensitivity is the ability of the screening instrument to generate a true positive result for someone with the diagnostic category of interest.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com