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The gene will receive high weight only if it provides additional predictive ability for disease beyond its association with AU/DU.
Although gluconic acid lactone showed high discriminate ability for disease status, this may simply reflect inflammation status and may not be specific for IBD.
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The panel of four kallikrein markers also has good predictive accuracy for biopsy outcome and aggressive disease, and tissue biomarkers (i.e., Oncotype DX Prostate Cancer Assay, CCP score) show promising ability for predicting disease progression.
In addition, the practical application of immunosensor was evaluated by analyzing CRP in real human serum samples, the recoveries obtained were within 95.3%–103.8%, indicating the immunosensor possessed potential application ability for practical disease diagnosis.
It has been reported that ROC analysis is able to determine easily ability for identifying disease at any cutoff.
Serum HBV DNA level is an ideal surrogate marker for antiviral therapies because of its independent predictive ability for CHB disease progression [ 25].
Additionally we will assess whether particular tests can be removed from the set of tests without losing any diagnostic ability for each disease.
Some studies have shown that carotid IMT could improve the prediction ability for cardiovascular disease over and above conventional coronary risk factors (7, 8).
Combining the BRS and conventional risk factors substantially enhanced the discriminatory ability for the disease in middle-aged and older Chinese population.
Family history and polygenic genotype scores from SNPs identified by GWAS have similar predictive ability for common diseases, but genotypes already outperform family history for many rare conditions [ 34].
These findings confirm the previous observation that ADA + MTX controls bone damage independently of its ability to control for disease activity [ 24].
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