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Subsequently, unbalanced 11q LOH and 11q aberrations data were combined into a single variable: '11q aberration'.
Here, we conducted an integrated analysis based on copy number aberrations data and miRNA-mRNA dual expression profiling data to identify breast cancer subtype-specific biomarkers.
The detection of fewer copy number aberrations in HPV16-positive lesions was furthermore corroborated by hrHPV-typing analysis of an independent set of CIN2/3 previously analysed by arrayCGH [ 21], which also demonstrated that the majority of CIN2/3 with HPV16 (81.8%) clustered together and showed relatively few aberrations (data not shown).
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Chromosome aberration data obtained for various types of mammalian cells after exposure to low and high LET radiation clearly demonstrate differences in the energy deposition pattern of both radiation qualities.
We evaluated our approach on a toxicity data set, a chromosome aberration data set, and the MUV data sets.
We evaluated our approach on a toxicity data set, a chromosome aberration data set, and the maximum unbiased validation data sets.
We tested the visualization approach on the Kazius Ames toxicity data set [10], the chromosome aberration data set compiled by Mohr et al. [6], and the maximum unbiased validation data sets [11].
For microarray DNA copy-number aberration data: " brca_scna_all_thresholded.by_genes.txt".txt
Our copy number aberration data was generally consistent with previously reported data [ 7, 16, 17, 19- 23].
The human higher order aberration data were measured up to and including 5th order Zernike polynomials.
Strehl ratios and modulation transfer functions (MTFs) were calculated from the wave aberration data.
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