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This aberration was found in lung (34.8%), ovarian (20.6%), and uterine ACs (7.7%).
Two of the twenty aberrations (patients 1 and 5) are found in copy number variation databases; one aberration was found in both G3 and G4 (patient 2), and one was found in G3 (patient 13).
In the brain metastases, a high degree of aberration was found on almost every chromosome, with the most common gains (> 30% of cases) at 1q, 5p, 7, 8q, 10p, 11p, 12p, 15q, 18, 20, and 22, and losses at 3p, 8p, 9p, 10q, 11, 12p, 13, 15, 17, and 18q.
The most frequent aberration was found to be a gain on 3q, observed in 21 out of the 23 patients (91%), more precisely the loci 3q25 q27 in 20 of the 23 of the PT (87%), and 21 of the 23 LNM (91%).
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The image most free of spherical aberration is found at this distance.
However, no such significance of the genetic aberrations was found in patients with a HR- tumor.
Moreover, an increased level of chromosomal aberrations was found in PBLs of colorectal cancer patients with a family history of cancer [ 14].
Furthermore, a seasonal difference in chromosome aberrations was found with more chromosome aberrations in the fall (after the spraying season), and mostly so among the persons who did not use gloves during re-entry activities [ 17].
Significant increase (P < 0.05) in the frequency of total structural chromosomal aberrations was found between OT group and HOT group from one side and between group OT and the control groups (NTC and HTC) from another side.
After 0.7 Gy of Fe ions, most complex aberrations were found to involve three or four chromosomes, indicating this is the maximum number of chromosome domains traversed by a single Fe ion track.
average of 20 aberrations were found in each patient on this study.
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