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Using the accelerating tube, which is an extended electrostatic immersion lens with axial symmetry together with magnetic quadrupole lenses to form an ion microprobe, it is possible to find conditions permitting the total aberration level to be reduced.
Positive relationships between exposure and aberration level were considered statistically significant, using one-tailed tests, if p < 0.05.
An ophthalmic adaptive optics (AO) imaging system is especially affected by pupil edge effects due to the higher noise and aberration level at the edge of the human pupil as well as the impact of head and eye motions on the pupil.
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The most popular technique developed to reduce the number of treatment combinations is the fractional factorial design; confounding in estimating the model parameters naturally results in various resolution and aberration levels.
Higher levels of pericentrin correlate with aneuploidy and centrosome aberration levels in AML [6], [7].
Of the 10 cases of Hodgkin's disease, four exhibited evidence of enhanced radiosensitivity with aberration levels at or above the cutoff point defined by the WRI controls.
Comparison of aberration patterns in irradiated and nonirradiated cultures and consideration of elapsed time after therapeutic exposures suggested that the observed increased aberration levels reflected individual features of the patients' radiosensitivity, rather than lesions induced by previous in vivo exposures.
In line with our observation, Schneeweiss and colleagues [ 13] found a highly significant correlation of maximum centrosomal aberration levels with axillary nodal tumor involvement and the absence of hormone receptors in breast carcinomas.
In addition to identification of chromosomal aberrations, individual-level allele frequency can also be used to identify an occurrence of cell mixture.
As many metastatic cancer cells exhibit aberrations in levels and functions of key apoptotic regulators, exploiting these alterations to induce tumor cell apoptosis offers a promising therapeutic target [ 3].
Rab25 may exert different effects dependent on the intrinsic expression patterns in different cell lineages, the presence of different underlying genomic aberrations, the levels of specific Rab25 molecular partners, the cargoes being transported in Rab25-containing vesicles or the response of cells to activation of the signal transduction pathways controlled by Rab25.
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