The phrase "aberration contributes" is correct and usable in written English.
It can be used in contexts discussing how a deviation from the norm or an anomaly plays a role in a particular situation or outcome.
Example: "The recent data shows that this aberration contributes significantly to the overall results, highlighting the need for further investigation."
Alternatives: "anomaly plays a role" or "deviation adds to".
In conclusion, they implicated Spry2 in regulation of TCL1-augmented ERK signaling and B-cell proliferation and suggested Spry2 epigenetic silencing as an aberration contributing to B-cell lymprogressionession.
During these events, a series of genetic and epigenetic aberrations contributes to the carcinogenesis, which will be potential biomarkers for early screening, surveillance and treatment of the dysplasia and adenocarcinoma.
A deeper understanding of the biologic and molecular aberrations contributing to the pathogenesis of CLL led to identification of novel prognostic markers such as immunoglobulin heavy-chain variable gene (IGHV) mutation status, leukemia-cell expression of CD38, ZAP-70, and CD49d, and cytogenetic abnormalities detected by fluorescent in situ hybridization (FISH).
These aberrations contribute to the ectopic expression of the EVI1 proto-oncogene.
Furthermore, our data suggest that telomeric aberrations contribute to Cr VI) induced cytotoxcitiy and genotoxicity, and may contribute to respiratory cancers resulting from Cr VI) exposure.
Genome-wide quantitative analysis of CNNLOH using the CNNLOH Quantifier method can help to identify recurrent aberrations contributing to tumor development in clinical tumor samples.
Studies of epigenetic modifications, predominantly DNA methylation, may further reveal aberrations contributing to tumor development.
Genetic aberrations contributing to concomitant FHIT loss and p53 stabilization in tumors need to be delineated.
Our results suggest that epigenetic aberrations contribute to NB phenotype, and that tumorigenic properties can be inhibited by reversing the epigenetic changes with 5-Aza-dC.
The authors conclude that tumor heterogeneity is probably driven by aneuploidy and that chromosomal aberrations contribute substantially to genetic intratumor heterogeneity.
