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A further study is required to clarify the "aberrant type".
Two "aberrant type" and two "scattered type" were analyzed.
The wild-type tumors in "aberrant type" may reflect this mechanism.
In positive p53 tumors, two types could be distinguished; aberrant type and scattered type.
Aberrant type (Fig. 2A) had widespread staining of 70% or more nuclei in the sample.
There was no relation with clinicopathological factors between scattered type and aberrant type (data not shown).
Similar(43)
In Brca1-deficient cells, Moynahan et al [ 12] believe that nonhomologous processes may promote aberrant types of repair.
And all mutant TP53 gene tumors, which were missense, had aberrant-type staining of p53 (P = 0.0003).
Tight junctions, as visualized by ZO-1 immunostaining, were most aberrant in type 1 VHL mutants, although tight junction disorganization was seen with type 2B mutants and to a lesser extent with type 2A mutants, but not with type 2C.
Intraparenchymal aberrant RHA (type II) and those which were involved by tumor should require en bloc resection of the vessel.
These span 745 mb of sequence and therefore the likelihood of CNV overlapping cancer-specific loci in a highly aberrant tumor type are high.
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