Sentence examples for aberrant modification from inspiring English sources

This implies that the aberrant modification of H3K9 results in a small decrease of adh1+ mRNA.

In process of AbSV infection, a variety of pathogenic cascades are activated including cellular necrosis and aberrant modification of hemocyanin and ferritin.

Aberrant modification of histones associated with DNA repetitive sequences has also been reported.

Aberrant modification patterns to chromatin have been associated with the onset and progression of both germline and somatic diseases, ranging from mental disorders to many cancers [4 6].

ER upregulation of the UPR and aberrant modification of protein disulfide isomerase (PDI) also occur in human tissues from sporadic ALS (Atkin et al., 2008; Walker et al., 2010).

In malignant cells, aberrant modifications through acetylation and methylation at the promoter regions of individual histones have been reported.

Still, aberrant modifications are observed in diseased cells, and the enzymes that regulate histone modification have become important targets in drug development programs.

Moreover, they are often found bound to chromatin without their substrate mark present, suggesting a 'guardian' function to 'protect' chromatin against aberrant modifications [ 73].

Aberrant modifications such as hyper-phosphorylation and changes in the glycosylation patterns are usually associated with human diseases and several cancers [ 24, 25].

These findings indicate that the slow growth of glc7-E101Q strains was not the result of protein instability or the accumulation of aberrant modifications to the Glc7 protein.

Increasing evidence indicates that histone aberrant modifications contribute to human diseases such as cancer, neurodevelopment disorders, neurodegenerative diseases, and pathogen infection.