Sentence examples for aberrant high from inspiring English sources
We can thus conclude that the MR calculation is a good method for finding motifs linked to aberrant high signals.
The aberrant high signals we observe on features displaying T7-bias motifs are the result of excess binding of labeled target molecules.
Thus, the possibility is being raised that endogenously expressed Mdm2 is actually preferentially involved in mono-ubiquitination of p53, whereas aberrant high expression of Mdm2 may result in poly-ubiquitination and degradation of p53.
For example, aberrant high expression of Chemokine (C-X-C motif) ligand 13 (CXCL13) in the thymus in aged (NZB × NZW) F1 (BWF1) mice may play a pivotal role in breaking immune tolerance in the thymus and in recruiting autoantibody-producing B1 cells and CD4+T cells during the development of murine lupus [24] [26].
In glioblastoma cell lines, miR-21, as an antiapoptotic factor, exhibits aberrant high expression, and knockdown of it resulted in the activation of cell apoptosis caspases [ 60].
CD70 is an ideal target for antibody-based therapies because of its aberrant high expression in renal carcinomas and non-Hodgkin lymphomas and its highly restricted expression in normal tissues.
Now involved in producing and business ventures (including the recent purchase of Miramax Studios from Disney), he looks back at the aberrant highs of his heartthrob days, the changing nature of stardom in Hollywood, the trade-off he has made between high life and home life, and the step-by-step effort behind his show business survival.
This indicates that the normal, low-amplitude γ noise is pharmacologically metamorphosed into an aberrant, high-amplitude γ noise.
NPC and EBVaGC are thus typical tumor models of an EBV-induced aberrant high-methylation epigenotype.
We selected three clones expressing increasing VEGF levels in vitro, previously shown to induce either normal (low and medium) or aberrant angiogenesis (high): V low = 11.0 ± 0.4 ng/10 cells/day, V med = 61.0 ± 2.9 ng/10 cells/day, and V high = 133.2 ± 9.7 ng/10 cells/day.
Constant proteotoxic stress is a frequent occurrence in cancer cells and is derived from an adverse external microenvironment (hypoxia, acidosis) and internally from conformationally aberrant oncoproteins, high reactive oxygen species (ROS) levels, genomic instability, and stoichiometric imbalances in multi-protein machines.
