Sentence examples for aberrant expansion from inspiring English sources

Likewise, neuronal protein inclusions are clinically observed in MJD and arise through aberrant expansion of the polyglutamine-encoding CAG repeat within the ataxin-3/MJD1/SCA3 locus [6].

Fagarasan et al. previously reported that AID deficiency leads to aberrant expansion of anaerobic bacteria in the gut, which induces hypertrophy of Peyer's patches and ILFs as well as activation of the systemic immune system [3].

Although AID deficiency was reported to lead to aberrant expansion of anaerobic bacteria in the gut, we found that gastritis development in AID−/− mice results from an autoimmune reaction rather than hyper responsiveness to gastric microflora.

Huntington's disease (HD) is a fatal neurodegenerative disorder caused by aberrant expansion of CAG repeat in the huntingtin gene.

Studies in both humans and mice suggest that chronic NK cell lymphocytosis results from an aberrant expansion of an immature NK cell population with functional deficits [ 79- 81].

Trichomes of these mutants are smaller, bloated and misshapen due to aberrant expansion of the stalk and branches [ 29, 30, 33, 35- 38].

Our data did not reveal any sign of clonal dominance or aberrant expansions even in the presence of CIS in the LMO2 or CCND2 proto-oncogene loci (Aiuti et al, 2007).

Human polyglutamine disorders such as Machado-Joseph disease (MJD) and Huntington's disease (HD) are caused by aberrant codon expansion of CAG trinucleotide tracts within unrelated genes encoding polyglutamine-domain proteins.

Integration site analysis in transduced brain tissues showed no aberrant clonal expansion and preferential targeting of neural-specific genes.

The samples were analyzed by flow cytometry (FACSAria, Becton Dickinson) in order to detect aberrant clonal expansion.

Notably, similar to the developmental defect detected in the SVZ of the NEP-specific Tsc1 knockout model (Magri et al., 2011), an aberrant SVZ expansion was observed in RGC-specific Tsc1 mutant mice that seemed to be present also in RGC-specific Tsc2 mutant mice, in which it was interpreted as astrogliosis (Way et al., 2009).