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Of those, seven patients were enrolled in cohort 3. Adverse events with a worst grade of 3 or higher considered related to gemcitabine or erlotinib occurring in the control cohort were anemia (grade 3; n = 1), febrile neutropenia (grade 3; n = 1), fatigue (grade 3; n = 1), and rash (grade 3; n = 1).
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He got a B- for his business plan, his worst grade in business school, though he cannot remember why (he thinks it was late).
The worst grade given out is a C (which high-end restaurants Le Cirque and Gramercy Tavern received).
Figure 2 shows the graphical representation of survival curves according to the worst grade of neutropenia in a time-dependent manner, allowing patients to be transferred from one group to another (Simon and Makuch, 1984; Richardson et al, 2003).
Table 3 shows the result of a Cox regression analysis for the association between overall survival and the worst grade of neutropenia, which was treated as a time-dependent variable.
Instead, we treated chemotherapy-induced neutropenia as a time-dependent variable; for each patient, the worst grade of neutropenia occurring between the beginning of S-1 treatment and time T>0 was defined as the value of the variable at T. The variable value for each patient could change over time according to the worst grade of neutropenia experienced by that time.
The median number of prior radiation treatments was 1 and the median number of prior chemotherapy treatments was 5.> Table 2 displays a summary of treatment-related adverse events (counts by worst grade per patient, and worst grade per patient across all toxicities).
Trained staff use a standardised protocol to grade diabetic retinopathy, which is an enriched version of the English National Screening Protocol, 20 and take the worst grade for either eye as the final grading level.
Moody's rating has now dropped one level lower than the worst grade during the state's recession a decade ago.
Worst: Grade inflation: In Morningstar's star system, nearly every fund is a winner.
The watchdog group Freedom House rates Belarus as "not free", and gives the country the worst grade possible when it comes to political rights.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com