Sentence examples for a widespread role of from inspiring English sources

Here, we provide evidence for a widespread role of Aub and piRNAs in maternal mRNA decay in the early Drosophila embryo during the MZT.

Thus there is broad support for a widespread role for impaired function of arousal and adrenalin systems in ADHD and the impulsivity that is characteristic of the disorder.

Several resulting phenotypes are partially rescued by mTORC1 inhibition, demonstrating a widespread role for mTORC1 activation downstream of APC mutation.

In addition, we suggest a widespread role for Math6 in the modulation of differentiation programs in various cell types during embryogenesis.

Aberrant activation of kinase signaling pathways in invasive breast cancer cells, however, may play a widespread role in failure of tamoxifen therapy [ 3, 5].

Furthermore, immunolocalisation of the AT1 receptor also strongly suggests that Ang II has a widespread role in maintenance of epithelial structure and function (Vinson et al, 1995, 1997).

This, although being a negative result, represents a major finding of importance to the field, since it essentially excludes a potential widespread role of GCs in translational gene regulation, at least in the investigated systems.

This suggests that age plays a widespread role in the expression of these pathways.

These findings suggest that KRAB-ZFP transcription factors may have a widespread role in transcriptional silencing of TSGs in cancer cells.

These cleavages are likely mediated by the P. acnes homologue of RNase III (Additional file 4), which is a well-characterised, double-strand-specific endoribonuclease [ 60] with a widespread role in the maturation of ribosomal RNA [ 10].

Finally, we show that patterns of splicing and alternative splicing of pri-miRNAs may be elucidated from whole transcriptome deep sequencing data and confirm that a significant proportion of grapevine pri-miRNAs are subjected to such processes, consistent with the suggestion that post-transcriptional regulation might play a widespread role in the regulation of plant miRNA maturation.