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Syrian forces gave artillery and air cover to the operation, which marked the powerful militia's first acknowledgment of a widespread involvement in Syria's war that has has steadily taken on a regional, sectarian dimension over the past year.
Present data therefore suggest a widespread involvement of TDP-43 in neurodegenerative disease beyond FTLD-U and MND.
This study has demonstrated a widespread involvement of the ROCK signalling pathway in early stage diabetic coronary dysfunction in vivo.
The former present as a nodule of small nests of tumor cells more commonly located in the epididymis and para-epididymal area, with a widespread involvement in the interstitium and the relative sparing of the seminiferous tubules [ 17].
Research conducted in recent years on adenosine-A3 receptors has shown a widespread involvement of adenosine-A3 receptors in hippocampal functions such as activation of phospholipase C (Abbracchio et al. 1995), modulation of LTP and LTD in CA1 (Costenla et al. 2001), and protective effects on the CA1 region after inhibition of adenosine-A3 receptors (Pugliese et al. 2006).
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In addition to p53 control, the positive regulation of GLI1 activity by the major human oncogenes (RAS, AKT; Stecca et al, 2007), and its negative regulation by the tumour suppressor PTEN (Stecca et al, 2007), highlights the exquisite regulation of GLI1 activity and provides a rationale for its widespread involvement in human cancer.
A unique finding in our study was the widespread involvement of gastrointestinal parasympathetic ganglia.
The clinical features and extent of defects can vary from a limited area on one tooth surface to widespread involvement, affecting multiple surfaces and teeth.
Widespread involvement of the cerebral cortex is also a characteristic feature [35].
To summarise, compared with the universal engagement with livestock and the widespread involvement with farming and off-farm work, only a small proportion of households received wildlife earnings in most sites (3% to 14%).
Similar to other phenotypic observations, the appearance of inter-acinar stromal fibroplasia was evident in transgenic mice over a year of age and consisted of more focal rather than widespread involvement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com