The phrase "a widespread induction of" is correct and usable in written English.
It can be used in contexts discussing a large-scale initiation or introduction of something, such as a policy, practice, or phenomenon.
Example: "The study revealed a widespread induction of new teaching methods across various educational institutions."
Alternatives: "a broad implementation of" or "a large-scale introduction of".
In comparison, shading caused a more widespread induction of genes responsible for protein ubiquitylation and degradation.
Indeed, some direct tissue damage may be caused through widespread induction of a respiratory burst in responsive phagocytes (14).
Despite causing a marked downregulation of these proteins, wild type EPEC infection was not associated with widespread induction of apoptotic/necrotic mechanisms.
These transcriptional changes are consistent with generation of oxidative stress and the widespread induction of compensatory cellular stress response pathways.
The widespread induction of MAPK genes in response to diverse stressors and hormones suggests that MAPK genes play a significant role in hormone signaling pathways during stress tolerance.
In previous reports, ourselves [13] and other investigators [14] have identified widespread induction of eRNAs following activation of the innate immune response.
While Kras G12D pancreata exhibited few or no PanINs at this time point, there was widespread induction of ADM, leukocyte infiltration, fibrosis, and PanIN initiation in Ptf1a cKO; Kras G12D pancreata.
Despite widespread induction of CYP1A throughout the vascular endothelium observed as early as 36 hpf (Table 1 and data not shown), the overt signs of pyrene toxicity do not appear until after 80 hpf.
Control of oxidative stress and suppression of the NLRP3 inflammasome may directly limit viral replication, or correlate with induction of a potent antiviral response that targets virus-infected cells before enough viral RNA is produced and recognized by PRR to lead to widespread induction of innate immune pathways such as IFNβ/α.
This select action of IL-1RI signalling differs from our earlier report in MyD88 KO animals, which displayed global defects in inflammatory mediator release (Kielian et al., 2007), which is likely explained by the more widespread induction of cytokines/chemokines emanating from the loss of both TLR and IL-1RI cascades.
