The phrase "a widespread effect on" is correct and usable in written English.
It can be used when discussing the broad impact or influence that something has on a particular subject or area.
Example: "The new policy has had a widespread effect on the community, improving access to essential services."
Alternatives: "a significant impact on" or "a far-reaching influence on".
Pater's early influence was confined to a small circle in Oxford, but he came to have a widespread effect on the next literary generation.
Finally, mainstream users will also crave DSL, and that will have a widespread effect on the entire telecommunications industry.
The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system.
It was felt unlikely that the explosion had a widespread effect on air quality at ground level.
Whatley hopes that the book will have a widespread effect on senior athletes and help create a "movement to get America fit".
Secondly, in the GHSR null mice we demonstrated a hyposensitivity to only CA (sour) and NaCl (salty) tastes, indicating that despite ghrelin and GHSR being expressed in all four TC types there was not a widespread effect on all taste qualities.
A widespread effect of HDAC inhibitors on microRNAs (miRNAs) levels was first reported in the breast cancer cell line SKBr3.
These observations suggest that selection on the inversion, which suppresses recombination over a large portion of chromosome 6 (Lee 2009), has a genomically widespread effect on SNP variation.
Perhaps more important, Japan agreed to reconsider its methods of setting the fees paid by N.T.T.'s competitors to use its network, which should have a more widespread effect on reducing fees and enhancing competition in 2002 and thereafter.
To determine if ICG-001 has a similar widespread effect on other cancer cells, we also examined pancreatic cancer cells.
Intriguingly, the whole mutation spectrum was increased, not only at CpG sites, suggesting that truncated MBD4 has a more widespread effect on genomic stability.
