In the Western United States, where the complexities of water law and heavily subsidized federal and state water projects have complicated the economics of water delivery and hamstrung any widespread development of water markets, the Carlsbad plant offers a peek into a future when water prices reflect the actual cost of procurement and delivery.
It is known that, despite this evidence for the effectiveness of CDSS, a widespread development, evaluation and implementation of CDSSs, especially in HF clinics, is lacking [ 19, 20].
A second factor has been the widespread development of the use of composite materials in aircraft structures.
Psoriasis is a chronic inflammatory disease that leads to widespread development of erythematous plaques with adherent silvery scales.
"Until ongoing efforts to reduce greenhouse gas emissions associated with the production of oil sands are more successful and widespread development of oil sands crude represents a significant increase in greenhouse gas emissions," the EPA's assistant administrator, Cynthia Giles, wrote in a letter posted on the agency's website.
However, many ErbB2-positive cancers exhibit intrinsic resistance, and the widespread development of acquired resistance to ErbB-targeted agents remains a substantial clinical problem.
The widespread development of resistance to cheaper antimalarial drugs means that a majority of individuals suffering from malaria worldwide are not receiving effective treatment.
With the widespread development of intensive care facilities in the 1950s and '60s, more and more such moribund patients were rushed to specialized units and put on ventilators just before spontaneous breathing ceased.
One woman, the most freely discursive voyager in the movie, looks at the valley and takes note of the widespread development of well-built houses, where, formerly, there were none, and then reminisces: "When I think of the old days, these times seem better.
