Sentence examples for a wide dose from inspiring English sources

In general, the MMAD of our optimized delivery setting was found to be about 3.7 ± 0.3 μm throughout a wide dose range (Table 1).

HN2 challenge was administered via the apical (air) interface over a wide dose range (20 400 μM) to differentiated HBE1 cells.

The two Phase 1 studies reported herein were designed to assess the safety and pharmacokinetics of AV-101, over a wide dose range, after daily dosing for 14-days.

Among the administration routes assayed, the hydrogels were well tolerated after oral administration of a wide dose range (10 500 mg/kg), thereby indicating that both PAMgA hydrogels are excellent candidates for oral administration due to their in vitro biocompatibility and oral non-toxicity.

Furthermore, the addition of free mannose per se, across a wide dose range, induced significant reduction in MO10 biofilm formation.

In different studies, lasofoxifene demonstrated linear pharmacokinetics over a wide dose range (from 0.01 to 100 mg).

These results demonstrate that USL255 provides consistent plasma topiramate exposure across an extended-dosing interval and predictable plasma topiramate concentrations over a wide dosing range.

Interestingly, recent in vivo studies, using a wide dose-range, suggest that even the "mixed" (i.e. with a fixed ratio of affinities) serotonin (5-HT) and norepinephrine (NE) reuptake blockers venlafaxine and duloxetine act mostly as selective serotonin reuptake inhibitors (SSRIs) after systemic administration [2].

Only BCNU, melphalan, nitrogen mustard, and the combination of thiotepa and cyclophosphamide demonstrated steep dose-response relationships over a wide dose-range.

This study provides evidence that Gelsemium s. exerts a prevalently inhibitory effect on a series of neurocyte genes across a wide dose-range.

Oxybutynin-ER has a wide dosing range from 5 mg to 30 mg.