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As a whole, linkage disequilibrium was observed around the HWC2 locus, supporting the result of the fine mapping (Fig. 1c).
The population was characterized by long crop genomic segments in a heterozygous state which sometimes spanned all the markers of a whole linkage group (Additional file 1: Figure S2A).
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A further study of the region, including a sequencing of the whole linkage region in larger sets of individuals, will be required to elucidate this hypothesis.
The IDBs covered a quarter of the whole linkage groups of B. napus that could align with the genome of Arabidopsis (Table 2).
The International Multi-centre ADHD GenetIMAGEIMAGE) project performed a whole genome linkage scan specifically designed to map ADHD quantitative trait loci (QTL).
We performed a whole genome linkage analysis for height in a population from northern Sweden and identified a region on chromosome 7 with a lod-score of 4.7.
A whole genome linkage study has implicated several potential non- HLA contributory loci/genes for BD [ 9].
In humans, a whole genome linkage scan performed in an isolated Nepalese population identified two loci with unequivocal effect on susceptibility to Ascaris infection (e.g. [ 31]).
To uncover the genetic basis of the impairment we then carried out a whole genome linkage study, candidate gene sequencing and copy-number variation analysis.
A whole genome linkage study, conducted in an Indonesian Thin Tail × Merino sheep population, has revealed QTL for birth weight on OAR5 and for body weight at yearling on OAR18 [ 16].
Based on a whole genome linkage analysis we screened SLC2A1, encoding the glucose transporter of the blood-brain-barrier, GLUT1 and identified heterozygous missense and frameshift mutations segregating in this and three other nuclear families with a similar phenotype.
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