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Activity in the GrC network, which receives direct mf input, is thought to represent key temporal components to drive a well-timed response (Medina and Mauk, 2000; D'Angelo and De Zeeuw, 2009).
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Recently, in collaboration with Javier Medina at the University of Pennsylvania, our laboratory implemented head-fixed recording methods for classical eyeblink conditioning in mice, achieving well-timed responses, learning over a time course of days, and consistency from animal to animal.
It is argued that savings results from plasticity in the deep cerebellar nuclei, but re-acquisition of well-timed responses (facilitated by savings) likely requires the cerebellar cortex (Medina, Garcia and Mauk 2001 J Neurosci).
Large deficits can be benign or even desirable during recessions and wars, or when used to finance productive public investments; and in a deep, long-lasting downturn, with interest rates at or near zero, a well-timed, sensible fiscal response can theoretically help in the short term.
Only on the condition that it is consistently paired with the air puff and only by virtue of the Purkinje cell's capacity to forge associations between parallel and climbing fiber signals will one learn to perform a well-timed, conditional blink response (CR) upon exposure to the light, which is thusly called the conditional stimulus (CS).
You can't stop Father Time, even with a well-timed Harlem Shake routine.
A well-timed pause.
A well-timed arm bar.
Enter Rudy with a well-timed endorsement.
A well-timed question to the sommelier.
Talk about a well-timed opening.
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