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The relatively small number of patients does not allow a well-founded genotype phenotype correlation.
Now there are thousands of exome and whole-genome sequences (soon to be tens of thousands, and eventually millions), which have been determined with the aim of identifying disease-causing variants and, more broadly, establishing well-founded correlations between sequence variation and specific phenotypes.
"It's a well-founded, pretty detailed M.O.U".
That is, we have failed to deliver them a well-founded feeling of security.
It's a well-founded fear given the Taliban's record of targeted killings.
There is a well-founded tradition of violece in the North.
Prerequisite for a successful support is a well-founded analysis of a hydraulic system's structure.
Broad specialist knowledge and a well-founded understanding of explosion protection are of benefit to all.
Thus the tolerance planning engineer can give a well-founded feedback to the departments involved.
The legal standard for being granted asylum is a well-founded fear of persecution if the person is sent back.
A well-founded clade within Stylopidia is Stylopiformia, which are characterised by a unique fissure-shaped birth opening.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com