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This may reflect the fact that our samples are from a well-defined stage of disease progression, that is, Dukes' C tumours.
Hence the association of TMs into pairs and bundles is a well-defined stage during theoretical and experimental studies of polytopic membrane protein folding [ 15, 16], and current models suggest that this process can occur within the context of the ER translocon, where cohorts of TMs may assemble before integration [ 17– 17].
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"You start with a well-defined state, and you end with a well-defined state.
All these elements are much more difficult to organize in one well-defined stage, but are indeed part of a process that stresses the participatory approach and comes under the third strand of the methodology being discussed.
This chapter explores how and why a typical project is organized in a number of well-defined stages.
Brain abscesses evolve through a series of well-defined stages, as revealed by MRI (magnetic resonance imaging) and CT (computed tomography) scans (Mathisen and Johnson, 1997; Gupta et al., 2010).
A performance of a raga usually goes through well-defined stages, beginning with an improvised melodic prelude that is followed by a composed piece set in a particular time measure.
The TV plot corroborates that the complete untreated fibrosarcoma Sa-37 TGK (i = 0) exhibits an S shape with three well-defined stages (SI, SII, and SIII).
Tensile creep curves are of classical shape, with a well-defined secondary stage of steady-state creep, for all except a few samples that were tested at higher temperature and lower stress; these display signs of extensive oxidation along the pore surface.
We have described a differential proteomic profile of a single plant cell type at a well-defined developmental stage, during which secondary cell wall biogenesis is occurring.
In particular, a well-defined narrow stage B also occurs in HPT-Ni due the removal of grain boundaries in the wake of pronounced crystallite growth in this stage [9], similar to Cu.
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