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We did not directly assess how many systematic reviews in our sample called for a change in clinical practice as we assumed that all our sources (ACP Journal Club, Evidence-Based Medicine, and the Cochrane Library) highlight newsworthy and relevant evidence through well established selection processes.
SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers.
Information gain is a well established measure for feature selection in Machine Learning.
Salt screening and selection is a well established approach for improving the properties of drug candidates, including dissolution rate and bioavailability.
Thus, it seems that a well established nucleosome depleted region, the UAS of Gal1 and Gal10, cannot be reproduced by MNase digestion, size selection and deep sequencing due to the systematic sequence-dependent measurement biases.
A trained architect, Hardwicke is a well established production designer.
The PSS is a well established measure.
Standardized extracts from a well established vendor were used.
Ocular damage from radiation treatment is a well established phenomenon.
DFO is a well established hypoxymimetic agent [ 26].
Solid tumors require a well established vasculature to grow.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com