The phrase "a well established base" is correct and usable in written English.
It can be used to describe a solid foundation or support system that has been developed over time, often in contexts like business, research, or community building.
Example: "The company has a well established base of loyal customers who trust its products and services."
Alternatives: "a solid foundation" or "a strong base".
It is now well established, based on a series of recent elegant studies using mouse genetics, lineage fate mapping techniques, and transcription profiling, that embryonic monocytes give rise to the majority of tissue macrophages in an adult animal except for in the intestine, heart, and skin [1-3].
Among others, the DNA damage theory of aging of HSCs is well established, based on the detection of a significantly larger amount of γH2AX foci and a higher tail moment in the comet assay, both initially thought to be associated with DNA damage in aged HSCs compared with young cells, and bone marrow failure in animals devoid of DNA repair factors.
(iii) Green building should not only be limited to energy performance-oriented, but also be user-oriented, the social and humanistic needs model is thus well established based on Maslow׳s Hierarchy of Needs.
The principles for the fixation and treatment of bone fractures have been well established based on the multidisciplinary studies performed by the Arbeitsgemeinschaft für Osteosynthesefragen/Association for the Study of Internal Fixation (AO/ASIF group).
While the fire behaviour of concrete-filled steel tubular (CFST) columns with circular and square cross-section has been well established based on experimental programs and numerical investigations, the information about the fire behaviour of CFST columns with rectangular or elliptical cross-section is very scarce.
The market for improving mental health through the use of VR has been well established based on decades of scientific research.
The buffering properties of the Ag/Ge(111 -√3 111 -√3rface may be accounted for in terms of its unique atomic arrangement, which is currently well established based on the experimental [8–14] and theoretical work [13].
The mechanism of pH-triggered release from nanocarriers based on polyelectrolytes was well established based on previous reports.
The close relationship between these three orders is well established based on morphological data [ 14, 15], but is currently uncertain based on phylogenomic data [ 16].
The biological relevance of G-quadruplexes is well established based on their formation in the telomere region and also in the promoter region of other oncogenes [ 22– 26].
