Moreover, treatment with Non-steroidal anti-inflammatory drugs (NSAIDs) which inhibit NFκB has the ability to reverse immunosuppression induced by a tobacco-specific carcinogen, in addition to their well established ability to decrease oral dysplasia as well as induction of overt cancer in transgenic animals [18].
In a comparative study, the authors show that HKUST-1 exhibits no difference between adsorption isotherms of CO and N2, despite its well established ability to coordinate other adsorbed gas molecules at the open CuII sites (see above).
10, 45 NSAIDs adversely affect the cardiovascular system in part through their well established ability to increase blood pressure (about 5 mmHg) 25 and in part through their effects on renal function.
Taking advantage of the well established ability of Agrobacteria tumefaciens to transfer a defined segment of DNA (T-DNA) to the plant nucleus [ 4], the molecular genetic modification of plants is most often performed using binary vector systems that separate the T-DNA from the trans-acting virulence proteins that effect the transfer [ 5].
High-volume HIT has a well-established ability to increase cardiorespiratory fitness to a greater extent than conventional endurance training in normal adults.
Solid tumors require a well established vasculature to grow.
For severity grading of dental erosion, a well established scoring system with the ability to diagnose early stages, as well as more advanced stages of erosion, was required.
It is well established that the ability to consume oxygen at a high rate is strongly linked to endurance exercise performance.
It is well established that the ability to recognize events with high confidence and to experience vivid recollection is critically dependent on the hippocampus (Vargha-Khadem et al. 1997; Eichenbaum et al. 2007; Ranganath 2010; Squire and Wixted 2011).
It is now well established that the ability to ignore irrelevant distractions is not determined just by the intention to be focused or by the separability of the target and distractor stimuli, but also by the level and type of processing load involved in the current task (for reviews, see, e.g., Lavie, 1995, 2005, 2010; Lavie & Dalton, 2013; Lavie & Tsal, 1994).
The role of microRNAs (miRNAs) in many human diseases is well established, and their ability to act as both therapeutic agents and disease prognostic biomarkers makes it important to understand this family of molecules [ 15].
