A weakness of this study was that one-quarter of the children dropped out before its conclusion.
Nonetheless, a weakness of this study and previous ones is that the women themselves decided whether to take hormones, rather than being assigned at random to take either drugs or placebos.
A weakness of this study was participant selection.
A weakness of this study is the lack of available level I evidence.
The lack of a validated biomechanical explanation of the pathomechanics of the LOE test is also a weakness of this study, and one that should be addressed by performing a deep clinical and experimental investigation.
A weakness of this study is the retrospective design and absence of a standardized functional outcome tool such as the UCLA shoulder score, ASES shoulder scoring scale, Constant Murley score, and disabilities of arm, shoulder, and hand (DASH) systems.
At the same time, this limitation can be considered as a weakness of this study because this paper covers not all available evidence on PPT measurement over the cranio-cervical region.
The limited number of patients is a weakness of this study and the results are preliminary, but promising, which stimulates further research using freeze-dried bovine xenografts as a bone substitute.
Therefore, a weakness of this study is the lack of samples to test independently the performance on stage I disease.
17 A weakness of this study is its retrospective nature.
A weakness of this study is the sample size.
