When a normal heart contracts to pump blood throughout the body, a wave of electrical signals flows through the heart, stimulating each cardiac cell to contract one after the other in a normal rhythm.
The attack last month and a wave of arrests signaled a return to the tough policies that were in place before Mr. Razali began his visits.
Finally, this primary activation and aggregation step is followed by a second wave of signals that lead to stabilization of the platelet aggregate [2].
Our data strongly support the view that resistance in Vitis riparia is a post-infection phenomenon, characterized by a rapid wave of signal transduction (12 hpi) followed by a shift in primary and secondary metabolism (24 hpi) to implement a defense mode.
Thus, their binding to GPCRs might initiate a second wave of signaling and represent a novel mechanism of GPCR signal transduction.
They clearly demonstrated that PTHrP possesses a double signalling on MCF-7: an antimitogenic pathway mediated by the membrane receptor and a second wave of signalling, pro-proliferative and antiapoptotic, based on nuclear localisation of the peptide.
These data suggest that beta-arrestin binding, which terminates receptor-G protein coupling, also initiates a second wave of signal transduction in which the "desensitized" receptor functions as a critical structural component of a mitogenic signaling complex.
These data suggest that β-arrestin binding, which terminates receptor G protein coupling, also initiates a second wave of signal transduction in which the "desensitized" receptor functions as a critical structural component of a mitogenic signaling complex.
The recent US Food and Drug Administration FDAapprovalval of belimumab, an inhibitor of B lymphocyte stimulator (BLyS), for the treatment of SLE patients has highlighted a new wave of signaling targets that are being therapeutically exploited with some encouraging results in lupus.
The election saw a wave of liberal victories that signals a shift in direction toward the core values Warren argues for.
