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XN led to a vigorous induction of HO-1 mRNA in WT, but not at all in Nrf2−/− cells.
During the initial phase of sepsis, a vigorous induction of the innate immune system can cause exaggerated production of pro-inflammatory cytokines, chemokines and other inflammatory mediators.
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Accordingly, using MBS extract might have advantage orver single active componnents in triggering two or three pathways of apoptosis simultaneously leading to vigorous induction of apoptosis.
Next, we took advantage of the fact that the isolated tandem WT 2CARD elicits a vigorous and spontaneous induction of downstream signaling [7] to examine whether S183I mutation could also inhibit this constitutive cell response.
Consistent with the previous observation of active HCV-specific T-cell response in biopsy specimens during resolving infections, we found evidence for a vigorous immune response involving induction of CD8+ T-cell markers (CD8 antigen and components of the T-cell receptor) and effectors of CD8+ T cells (granzyme A and interferon-gamma) in X0190.
In response to the untreated porcine bone and cartilage (group P1), there was a vigorous production of IL-1, IL-6, IL-10 and TNF-α, while no induction of IL-4 or IL-12 was seen.
Despite previous evidence that activation-associated caspase-3 induction does not drive the death of cells in vitro (18, 19), the prospect that a vigorous outgrowth of small population of caspase-3low cells might mask a significant level of dying caspase3hi cells remained a possibility.
He proposes a vigorous version of the free market.
Expressed a vigorous strain of the national character.
And he was a vigorous supporter of the Russian poor.
Like the United States, South Africa has a vigorous culture of plea bargaining.
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