Sentence examples for a very upstream from inspiring English sources
Csk inhibition alone induced some ligand-independent TCR downregulation, but additional downregulation was observed with all peptides, even the weakest G4, which argues for altered signaling of low-affinity peptides at a very upstream step.
Frame analysis should, therefore, be deployed at the very upstream level, when a given technology is emerging as a potential opportunity to be considered for future investments.
Only CG6128 has available alleles within the gene; both are P-element insertions within a very large upstream intron.
This study focuses on the Plassac Tidal Bar, which is the unique lobate-shape tidal bar of the Gironde Estuary, located at the very upstream extremity of the bay-head delta, because no detailed sedimentological studies have been made on such geomorphological category of tidal bar.
Combined together, our analysis suggests that it is critically important to identify key firms located at the very upstream of the conflict mineral supply chain and to regulate transactions associated with these firms.
In contrast, global mRNA expression profiles are very upstream phenotypes that hint at specific biological mechanisms.
Finally, we identified SALL4, one of the very upstream TF in the specification of different blastocysts derived stem cell lineages [46] and important in the stem cell network [47] [49].
Some of the very upstream molecules regulated by Wnts have been identified.
In another study, the RhoA/ROCK1 module was found to regulate the very upstream component of the Mek/Erk pathway.
Finally, the model is compared with NASA's experimental results for two outlet guide vanes at approach condition, showing a very good agreement upstream, whereas an underestimate of 3 5 dB is observed downstream in the middle frequency range.
