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This resulted in a very subtle increase in vascular permeability with time in both wild-type and Mac-1-/ mice (Figure 1F).
Removal of sulfoxide results in the residuals increasing by a factor of 2, however, removal of the sulfinic acid component results in only a very subtle increase in the residual.
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As shown in Figure 1 B, only very subtle increases in interstitial fluorescence intensity were observed during the 30 min superfusion of the cremaster preparation with bicarbonate-buffered saline (vehicle), indicating that the basal leakiness of the microvasculature to albumin was very low.
Within 72 h of initiating mechanical stimulation we found that bone marrow cells adjacent to the displaced implant exhibited a very subtle yet reproducible increase in proteoglycan-rich extracellular matrix (n = 5; Fig. 2A,B).
Therefore a function during growth could reasonably be posited but must be a very subtle one.
In a very subtle way".
"This is a very subtle process".
But that's a very subtle tweak.
It's a very subtle art.
That's a very subtle thing".
It's a very subtle performance".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com