Sentence examples for a very substantial manner from inspiring English sources

However, the present work from the Emr group extends these findings in a very substantial manner by showing how the ubiquitin-driven endocytosis machinery (involving the Art protein family members and the ubiquitin ligase Rsp5) surveys the plasma membrane for defective proteins and removes them.

It is a very substantial legacy.

We've built a very substantial audience.

"There is a very substantial moral hazard in that".

I have a very substantial chance of winning.

"It's a very substantial decision," he added.

But all this represents "a very substantial workload in an already very stretched sector.

And the result is a very substantial spike in prices with fairly substantial negative consequences to the economy.

So the outcome is a below-market loan to complete a very substantial rehabilitation.

He said: "It would be an ongoing accumulative value... a very substantial financial value".

Keeping them is a very substantial opportunity.