Exact(1)
In APP knockout neurons, a very significant up regulation of APLP1 (150 ± 6%, n = 3) but not APLP2 was observed (Supporting Information Fig 3C), suggesting partial compensation of absent APP by APLP1.
Similar(59)
No significant difference in the expression of let-7 and miR-200 famiRNAsiRNAs was observed in MCF7TR cells, relative to MCF-7 cells; however, a very significant up-regulation (more than 7-folds, p < 0.01) of miR-10b expression was seen (Fig. 1b).
We have also shown that the projection effect is unpredictable and could sometimes be very significant (up to 100% of the velocity measured in the LASCO field of view).
It is a very significant step up in his own career.
"Investors who have been relaxed about this are going to get a very significant wake-up call if they're not careful," Mr. Shepherdson said.
"I think what we're seeing in Australia is very much the focus on acquiring premium, highest quality, high-value brands that will enable a very significant mark-up or profit with the wealthiest element of Chinese society".
"It's a very significant as yet unresolved question".
These findings are consistent with the observation that there is a very significant similarity of up-regulated genes in the swm1Δ strain to up-regulated genes in the clr6-1 seeabovesee andve and Table 1).
Further analysis, using hyper-geometric distribution tests, with a database of genes affected by histone modifications, showed that there is a very significant similarity of up-regulated genes in the swm1Δ strain to up-regulated genes in the clr6-1 seeain (see Table 1).
"The cardinal himself has played a very significant role in standing up to a lot of people — both internal and external forces saying Catholic schools have to close," said Joshua Hale, executive director of the Big Shoulders Fund, a nonprofit that supports inner-city Catholic schools.
"I think more and more places are welcoming solo diners because they make up a very significant percentage of the restaurant-going public," says Russell Norman, the restaurateur behind London's Polpo, where diners can prop themselves up at a bar and work their way through plate after plate of delicious Venetian tapas-style dishes.
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