The phrase "a very significant scale" is correct and usable in written English.
It can be used when discussing the magnitude or importance of something, often in contexts like research, projects, or events.
Example: "The study was conducted on a very significant scale, involving thousands of participants across multiple countries."
Alternatives: "a considerable scale" or "a large scale".
"I wanted to draw your attention to the rolling out of the oil-for-goods deal, which is on a very significant scale," Ryabkov told a briefing with members of the upper house of parliament on the talks with Iran.
"Although the loss of jobs is of a very significant scale, it is clear that BAE Systems foresee an important future for shipbuilding in Glasgow and we must all work towards securing the maximum possible economic benefit for Scotland".
There will always be some debate at the boundary, but key statistics such as beds; staff numbers; admitted episodes; and even emergency-department, outpatient and community-health services numbers, show very significant scale differences.
With such a large scale, noise exists to a very significant extent across the spectrum.
Indeed, if one can divide by several-fold the production scale this will represent a very significant reduction of the costs.
But Sorokin found that "the NEJM's interest in maintaining the confidentiality of the peer review process is a very significant one... and tip [sic] the scales in favor of the NEJM".
On the one hand, they are a very significant subject for urban agriculture globally in terms of the sheer scale of their production.
"In order to generate the scale at which we operate our business, having a very significant market share is critical".
"My view is we are still waiting for a very significant and tangible expression to implement labour market reforms, product reforms, pension system reforms which – given large scale fiscal stimulus is not available – is necessary to stimulate growth".
