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The phrase "a very significant role" is correct and usable in written English.
It can be used to describe someone or something's level of importance or impact in a specific situation or story. Example: "The protagonist's actions played a very significant role in the outcome of the story."
Exact(60)
played a very significant role in Leave winning".
"Labor will play a very significant role in the caucuses.
Foreign buyers have played a very significant role.
Mr. Snider, he noted, "has played a very significant role in our progress".
Inherent material damping plays a very significant role on dynamic behaviour of rotors.
Welding input parameters play a very significant role in determining the quality of a weld joint.
In this context, active power filters play a very significant role for improvement in power quality.
This in turn will require the independent reviewer to be given a very significant role in their appointment.
Environmental factors play a very significant role in addition to many medical comorbidities that are usually associated with aging.
The laser welding input parameters play a very significant role in determining the quality of a weld joint.
The development of BNCT at IRT plays a very significant role in the plan for sustainable application of the reactor.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com