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The phrase "a very significant part" is correct and usable in written English.
It can be used to emphasize the importance or relevance of a specific component within a larger context.
Example: "The research findings indicate that a very significant part of the population is affected by this issue."
Alternatives: "an important aspect" or "a crucial element".
Exact(49)
Russian culture will lose a very significant part of itself".
"Now it's a very significant part of our business".
This was a very significant part of my life.
Richard Batchelor, who has died aged 84, played a very significant part in this revolutionary development.
"To be home at night is a very significant part of being a father".
"Licensing is a very significant part of television as a whole.
Similar(10)
Max Castro, a sociologist at the University of Miami who studies the Cuban-American community, said he thought "a very significant percentage" of Cuban-Americans took part.
Another very significant part of the pattern is the existence of a father figure within the squad, to help guide.
Control of railway noise is very significant part of the urban traffic policy.
MR: Yeah, we got to that very significant part of the interview where we were talking about The X-Files.
Speaking to the Guardian before he left for White House talks on the Middle East peace process, Blair said that his 700-page memoir showed New Labour would in time come to be seen as a "great reforming government" in which Brown played a very significant positive part.
More suggestions(16)
a very salient part
a very considerable part
a quite significant part
a very significant proportion
a very huge part
a very appreciable part
a very vital part
a very vast part
a very tangible part
a very significant player
a very large part
a very poor part
a very significant breakthrough
a very moving part
a very significant case
a very homogenous part
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com