Sentence examples for a very significant block from inspiring English sources

As was the case for wild-type pol β, the BPDE-adducts posed a very significant block to polymerase progression, with catalytic efficiencies dropping nearly 5 orders of magnitude.

This is a very significant book.

As was the case for wild-type pol β, these BPDE adducts posed very significant blocks to polymerase progression, with catalytic efficiencies dropping between 3 and 6 orders of magnitude.

Authigenic clay minerals can become a very significant pore-blocking mechanism and may act as a cementing agent when present in an abundant amount.

The consumer blocking of advertising is a very significant opportunity, and it is a significant risk if you choose to ignore it".

Similarly to the intra-block alignment case, we have experienced a very significant decrease in the energy of the components orthogonal to the first eigenvector (around 4 5 dB) by doing this inter-block alignment.

So therein lies a very significant problem".

We have lost a very significant amount".

It is a very significant breakthrough.

It was a very significant shock.

"It's a very significant disablement step".