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Of course the trade-off between sensitivity and specificity should be kept in mind: a very sensitive method is useless when it is not specific enough and vice versa [ 29].
Fluorescence spectroscopy is not a very sensitive method, containing fluorophore (George et al. 2010).
The DCFDA fluorescence is a very sensitive method to detect the ROS level inside the cell.
Impedance spectroscopy is a very sensitive method for detection of non-stationary charge transport governed by charge-carrier relaxation in disordered semiconductors structure.
MRI is a very sensitive method of displaying bone lesions but, in the absence of localizing symptoms, it is not yet a practical method of routine skeletal imaging.
The presence of the anatase phase was clearly shown by micro-Raman spectroscopy, which is a very sensitive method to detect this TiO2 phase.
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NOEC and LOEC (no and lowest observed effect concentrations, respectively) are toxicological concepts derived from analysis of variance (ANOVA), a not very sensitive method that produces ambiguous results and does not provide confidence intervals (CI) of its estimates.
Therefore, a second, very sensitive method such as immunodetection on 2D-PAGE, was chosen to confirm the results of the broad range proteome approach and to investigate whether known antigens in RA (e.g. fibrinogenβ (Fibβ), fibrinogenγ (Fibγ), fibronectin and vimentin) are present in these complexes.
If our dilatation hypothesis is correct, the transient kinetics of bleached actin relocalization constitute a novel and very sensitive method for probing the cytoskeletal dynamics in leading edge micro-environments which are otherwise very difficult to directly interrogate.
Thus, the comparison between the two studies indicates that spinal DTI is a reliable and very sensitive method for detecting anatomical tract defects at spinal level.
This is a specific and very sensitive method among others (eg phasmatometric, nonflame molecular absorption, netronic activation, volumetric method) detecting Se at a quantity of 0.002 μg and is considered the method of choice throughout Europe (Thorling et al, 1986).
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