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"It's an outlier because we are curing people of a horrible disease in a very rapid time frame," John Milligan, Gilead's chief operating officer, said on a call with analysts on Wednesday.
Those percepts with a very rapid time course may be studied with the aid of instruments known as tachistoscopes that permit the durations of visual stimuli to be precisely controlled.
"Ideally, we will be able to analyze the isolates in the context of everyone else's data to see what's going on at a larger scale, and we want to do it on a very rapid time scale," Loman says.
Another appealing feature is that basic development occurs within days, a very rapid time frame compared with mammalian systems, and one that allows researchers to conduct multiple experiments within a short period of time.
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"It's moving along at a very rapid clip".
Thanks to the workings of these closely coupled mechanisms, at multiple stages and at very rapid time scales there are opportunities for the evolution of the intention, in at least two ways.
The goal was to look in a sample that was stimulated only once rather than after high frequency stimulations to avoid bulk endocytosis, and to look at very rapid time scales that would distinguish clathrin-mediated endocytosis from kiss-and-run endocytosis.
"They have a very rapid generation time for an animal--about 4 days," she says.
The statistical power to detect various rates of MD change (expressed as a multiple of the SD) for given numbers of examinations is shown in fig 2. Detecting a very rapid rate (four times the SD of MD variability) of change with 80% power requires between four and five examinations.
Historically, there was a very rapid rise between 1918, a time of troubles, and 1930, when the national herd reached levels approaching those of modern times.
A very rapid growth rate (doubling time less than 1 month) is more suggestive of a benign lesion and, in this case, a course of antibiotics followed by CT 1 month later can be performed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com