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Pancreatic cancer is one of the most lethal malignancies and is associated with a very poor overall survival, and surgery remains the only option for the possibility of cure for patients with localized pancreatic cancer [1].
Ductal adenocarcinoma of the pancreas (PDAC), a dismal disease with a late clinical presentation and a very poor overall prognosis (Yeo et al, 2002), seems to be an interesting subject to investigate with regards to the involvement of stem cell-associated genes and Hiwi in particular.
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Prognosis of metastasized disease has remained very poor overall, with improvement essentially being restricted to younger patients.
The prognosis for liver cancer is very poor (overall ratio of mortality to incidence of 0.95) [ 12].
However, patients suffering from oesophageal cancers and bearing EpCAM-positive DTCs had the worst prognosis with very poor overall survival and the presence of lymph node metastases (Driemel et al, 2013).
The rules themselves have very poor overall accuracy, but they led to improvements over the baseline BN accuracy on both datasets with statistically significant improvements on CDC-Sublineage and SITVIT-CV.
While SCLC is mostly chemosensitive in frontline therapy, the inevitable disease relapse in most patients and the subsequent chemoresistance remain formidable problems leading to very poor overall outcome (Ma and Salgia, 2004).
Furthermore, compared with patients with non-metastatic disease, the survival probability of patients with stage IV disease is very poor overall, and the mostly very short survival times are influenced by additional factors, such as surgical treatment of metastasis (Dahabreh et al, 2011).
The very poor overall utilization of maternal care and the relatively high neonatal mortality rate in Bihar state of India, as reported in this paper, emphasise the need for particular attention to achieving provision of maternal and newborn care to a much higher proportion of women than the present level.
The exclusion criteria for both overall and event-free survival were as follows: (i) exposure data from original study not found; (ii) vital status unknown; or (iii) child was less than 1 year of age at diagnosis (because of very poor overall survival in this age group together with short time to be potentially exposed to ELF MF before diagnosis).
But, approximately 1 in 35 patients develop metastatic tumors, and metastatic melanoma has a very poor prognosis with an overall survival between 8 to 18 months.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com