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The phrase "a very modest interaction" is correct and usable in written English.
It can be used to describe an interaction that is not overly significant or impactful, often implying simplicity or lack of extravagance.
Example: "The meeting was brief and informal, resulting in a very modest interaction between the two parties."
Alternatives: "a rather simple exchange" or "a minimal engagement".
Exact(1)
However, in our study, where NOS2 was the gene of interest, we found no interaction between LPS and FK565 in macrophages, and only a very modest interaction in VSM cells.
Similar(59)
At the point of treatment (0 h), we can see that the pathway undergoes a very modest reduction in flux along its length, attributable to the flux lost through the interactions competing for each metabolite.
I asked for a very modest £700.
He's a very modest, efficient mover.
"He's just a very modest fellow..
That is a very modest start.
poverty & a very modest level of living.
"Both come from a very modest background," Mostert said.
"My dad was a very modest man," Cook said.
He called it "a very modest step".
That turned out to be a very modest target.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com