Sentence examples for a very major issue from inspiring English sources

That's clearly a very major issue that needs to be looked at, and I've spent time on that as well.

"It's not a very major issue for me," he said.

This was a very major change.

She was a very major saver.

Antley had an admitted substance abuse problem; this was very likely a major issue in his death.

Human Machine Interaction HMII) has been a major issue since the very early phase of car development.

ICU organizational aspects therefore are very important and could be a major issue in decreasing physicians' depression.

DCA, as described in the IAEA manual, can be used to assess dose up to 4 6 weeks post-exposure quite accurately but throughput is still a major issue and automation is very essential.

It's more frustration rather than a major issue, because they've been very competitive in all their matches.

A A major issue involves service animals.

"It's a major, major issue.