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However, some RNAi treatments stood out clearly and resulted in very strong G1 increase FACS phenotypes while having a very limited effect on gene expression, effectively uncoupling transcription from cell-cycle progression.
In terms of practical impact, some feel that the debates have a very limited effect.
"Industry figures are where they were before the crisis, which had a very limited effect".
With the world becoming increasingly dependent on deepwater oil supplies, the BP spill has so far had a very limited effect on drilling around the world.
"Perhaps most troubling is that the massive tax rebates that were sent out during the April/mid-July period are having only a very limited effect on consumer spending," wrote Brian Bethune, an economist at Global Insight, a research firm.
"It seems that the measure will mainly benefit record producers and not performing artists, will only have a very limited effect for most of the performing artists" and "will have a negative impact on the accessibility of cultural material" for consumers.
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These might be additional common variants with very limited effect size, or rare variants with a higher effect size.
Recent published works have demonstrated that unmeasured/unknown confounding effects could be estimated by measuring the association between the exposure variable (heavy alcohol use in this case) and a proxy outcome, on which the exposure has no or very limited effect [ 17– 20].
But thus far, those efforts have had very limited effect on Chinese policy.
Policy responses will have very limited effect in stemming the US economy's deceleration toward stall speed: even with only a mild fiscal drag on growth, the US dollar is likely to strengthen as the eurozone crisis weakens the euro and as global risk aversion returns.
These results suggest that octanoate can be rapidly removed from the circulation with only very limited effect on SIG.
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