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The phrase "a very large proportion" is correct and usable in written English.
It can be used when discussing a significant part or percentage of a whole in various contexts, such as statistics, research, or general observations.
Example: "A very large proportion of the population supports the new policy, indicating widespread approval."
Alternatives: "a significant majority" or "a considerable share".
Exact(59)
We still import a very large proportion of our desserts.
"I'm talking about a very large proportion of the prison population".
The scientists were annoyed that "a very large proportion of the competitors shirked the examination".
They quickly incinerated more than 3,700 homes and, Mr. Garamendi said, "a very large proportion" of them were underinsured.
In an interview, Craig Landau, Purdue's C.E.O., told me, "A very large proportion of Purdue's R. & D.
"A very large proportion of the population has no interest, knowledge or time to direct their 401(k) plans.
Clearly, a very large proportion of the people who cross land and sea in the desperate effort to reach Europe are Eritreans.
I think that it's important to look at in the sense that [it affects] a very large proportion of the world in one way or another.
A very large proportion of the new user-facing features touch the cloud in some way, as a conduit or as storage.
Such schools still educate a very large proportion of the nation's children – a key factor in the UK's apparent loss of ground in the global education rankings.
"Kids with disabilities make up a very large proportion of the kids who are in the juvenile justice system, so it's a very, very disturbing finding".
More suggestions(15)
a very large prevalence
a very large participation
a very large amount
a very large percentage
a very large part
a very large proportionate
a very large extent
a very large ratio
a very large fraction
a very large majority
a very large incidence
a very large representation
a very large figure
a very significant proportion
a very substantial proportion
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com