The phrase "a very large issue" is correct and usable in written English.
You can use it when discussing a problem or concern that is significant in size or importance.
Example: "The environmental crisis is a very large issue that requires immediate attention from governments and citizens alike."
Alternatives: "a significant problem" or "a major concern".
The supply of ideas and brainpower, however, is a very large issue.
"Keystone is not a very large issue in the context of energy or climate change policy for the U.S.," said Robert Stavins, the head of the environmental economics department at Harvard University.
It is appropriate, however, to continue the conversation about the separation of church and state, because it too is a very large issue.
The next round may stir more controversy, Henn warned, because trash collection is "a very large issue for the city" that some people consider "sensitive". In the city's 2010 resident satisfaction survey, 92% of residents said they were "satisfied" or "very satisfied" with their trash collection.
Though hygienic design and operation of process equipment in dairy plants encompasses a very large number of issues, two critical aspects are correct selection of the material of construction for dairy equipment and specification of surface finish.
In addition to the unresolved issues which arise in the context of the preceding fallacies, there are a very large number of other open issues which seem to us unlikely to be resolved without the input of professional evolutionary biologists.
The group, ScienceDebate2008, said in a statement that voters needed to know candidates' views on science, given that "science and technology lie at the center of a very large number of the policy issues facing our nation and the world".
"There turned out to be a very large number of very complex and very difficult issues to solve related to how one would do that," Fukuda said.
"This is a very, very large issue to try to tackle in one hourlong panel discussion," Belgau said with a laugh, and a bit of understatement, during a phone interview from his home in Washington state.
