The phrase "a very large ensemble" is correct and usable in written English.
It can be used when describing a group or collection that is notably big, often in contexts like music, statistics, or collections of items.
Example: "The orchestra featured a very large ensemble, with over a hundred musicians performing together."
Alternatives: "an extensive group" or "a massive collection".
This is clear by examining the condition with a very large ensemble of myosin heads that work together to propel the actin filament.
As future studies, we plan to use the induced models, generated using the second strategy, to select the most promising subset of snapshots, out of a very large ensemble, for a given ligand.
Because muscle contraction is due to the action of a very large ensemble of actomyosin motors it is necessary to use statistical models to relate contractile properties, such as force-velocity relationships, to actomyosin interaction kinetics and mechanics [ 1, 105– 108].
In some of these low intensity samples, Monte Carlo sampling leads to very large ensemble standard deviations of the estimated primary parameters.
In contrast, in the current implementations of the two other similarity scores the algorithms require all pairwise RMSDs, the calculations of which may become prohibitively expensive for very large ensembles.
Because observations of in vitro assembly reactions typically are based on very large ensembles of molecules, interpretation of assembly kinetics requires particular care.
A large number of different null matrix configurations are possible for a given input matrix and we may wish to avoid undersampling ; however, at the same time very large ensembles can make the calculation of significance computationally intractable.
However, it is challenging to relate single molecule mechanics data to mechanics of muscle cells or myofibrils where very large ensembles of myosin motors interact simultaneously with the actin filaments (see below).
This procedure is applied several times so to construct an ensemble consisting of a very large number of surrogated samples.
