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The phrase "a very large consequence" is correct and usable in written English.
It can be used when discussing the significant impact or result of an action or event.
Example: "The decision to cut funding had a very large consequence on the community's access to essential services."
Alternatives: "a significant consequence" or "a major consequence".
Exact(1)
Dr Philip Tucker, part of the research team in Swansea, told the BBC: "It was quite a substantial decline in brain function, it is likely that when people trying to undertake complex cognitive tasks then they might make more mistakes and slip-ups, maybe one in 100 makes a mistake with a very large consequence, but it's hard to say how big a difference it would make in day-to-day life".
Similar(59)
As a consequence, small variations in the opinions had a very large effect on the Pearson correlation coefficient.
"The bottom line is that a very short delay in global action would have very large consequences for the ability to meet these very aggressive targets, even if very globally coordinated and ambitious action happens post-2025," SandersonerSanderson
Yellowstone volcano eruption is one of those events with very small probability yet very large consequences.
On most college campuses, where beer bongs are most popular, use or possession of such a device can carry a very large fine if not other stiff consequences.
This fact allows us to take into account a very large variety of processes, still finding potentially measurable consequences.
The consequence is that we have a very large number of informative SNPs, with relatively low coverage per SNP.
Uncertainty, it said, had "a very large impact on investment" and "on real GDP" and significant consequences for investment.
The consequences of living in what she calls "a very large, very coveted piece of real estate" have transformed Sherpa lives.
The high level of strain diversity may be a consequence of a high rate of genetic change and/or a very large population size.
A consequence of these technical improvements is the need to reduce a very large amount of area detector data within a short time.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com