The phrase "a very large aggregate" is correct and usable in written English.
It can be used when referring to a substantial total or collection of items, data, or elements in various contexts, such as statistics, economics, or general descriptions.
Example: "The study revealed a very large aggregate of data points that contributed to the overall findings."
Alternatives: "a significant total" or "a massive collection".
The impact of ethnicity on key parameters cannot therefore be established, although the proportions in each individual ethnic group would not yield a big enough sample to be useful, even with the very large aggregate sample size.
But, depending on how donations from individuals and political action committees are counted, the limits do not stop some businesses from making very large aggregate contributions.
On some key issues, such as the reassignment of the.org domain and on specific Top-Level Domain extensions, Internet user community members posted very few substantive comments, despite the very large aggregate number of postings, to the public message boards.
These results suggest that gelation of ionomer solutions at particular concentration thresholds is not due to an abrupt change in the aggregate structures at some critical concentration but occurs as a result of interactions between the very large aggregates that the OAM predicts should gradually form as the ionomer concentration increases.
The DNA loops plus the nuclear substructure constitute a 'nucleoid', a very large nucleoprotein aggregate generated by gentle lysis of a cell at pH 8 in non-ionic detergent and the presence of high-salt concentration.
Furthermore, the very large aggregates of nano-ZnO were not observed.
AFM images of CA, obtained after incubation at 52°C indicate that this enzyme forms very large aggregates of several microns in size upon such treatment (Fig. 8A).
In addition, the formation of very large aggregates would be expected to obstruct small capillaries, such as those in the lungs, leading to pneumonia-like symptoms.
Since each platelet has ∼80,000 copies of integrin αIIbβ3 on its surface [8], very large aggregates of platelets can rapidly assemble at the site of platelet activation.
