The phrase "a very different atmosphere" is correct and usable in written English.
You can use it to describe a setting or environment that contrasts significantly with another.
Example: "When we entered the new café, we immediately noticed a very different atmosphere compared to the bustling diner we had just left."
Alternatives: "a completely distinct ambiance" or "a markedly different environment".
Taken in 1979 at a Southern California beauty pageant, these pictures project a very different atmosphere.
Returning a few minutes later to fetch a forgotten coat, I discovered a very different atmosphere.
The Park Avenue Armory, that gargantuan pile on the Upper East Side, has a very different atmosphere.
His program resembles the agenda of the Islamist student groups but "we are creating a very different atmosphere," he said.
Saturday Twickenham had been more or less full, and charged with a very different atmosphere from the Six Nations norm there.
Speaking at rallies all over the country with the poet Habib Jalib, we encountered a very different atmosphere from that in Europe.
The album was conceived as a "rowdy pop record", both in response to Rough Trade's request for "one of those pop records like you used to make" and as a result of the "very different atmosphere" the band encountered at shows on the Love Kraft tour when the 'slow' songs from that album were played.
A lunar expedition would be of some value in learning how to live on the Martian surface but would not help us learn how to descend through Mars' very different atmosphere or use that planet's atmospheric resources effectively.
Anwar Saeed, a professor at the National College of Arts, works in a very different studio atmosphere from Ms. Khan's: a small, excruciatingly spare room on the third floor of a walkup in the city's old town.
Old Montreal and the Plateau have very different atmospheres but both share a sense of history, of being built to human scale, and in so being enabling and encouraging social interaction and a powerful local identity and sense of place.
The gallery is now a colony of interconnected spaces of varying sizes and very different atmospheres, which the exhibitions in the rolling programme will match.
