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In a verification set of 97 UC, Gui et al. reported 5% to have a non-silent point mutation of MLL3.
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The Nash Sutcliffe (N S) coefficient of efficiency was used to assess the quality of prediction of the verification set as a function of the length of the calibration set.
A verification sample set consisting of 25% of all samples in the study was randomly selected and the identification of this set was blinded.
For verification, a set of selected miRNA probes were used to perform a northern blot analysis for two normal and two cancer samples.
As for L-ANN, the aim of training algorithm is to minimize the RMSE of verification set [22].
The optimal network parameters were selected according to the RMSE of verification set.
This experiment is repeated k times, for each of the k possible selections of the verification set.
All available 102 samples previously analysed by 2D-DIGE were measured with the protein biochip: 21 pairs of the discovery set and 30 pairs of the verification set.
When only RTTs are used in training step, at verification step, a set of collected RTT involving a target host H, may be associated with multiple classes so multiple hosts may be predicted as target and not only host H—, because many probing hosts may experience similar RTT values.
Validation for irradiation status and for tumour pathology was performed for all of these family members, using medical records for pathology verification and a set of criteria that were used in previous studies (Sadetzki et al, 2005b) for irradiation verification.
The potential of both models was also validated on two independent verification sets: one consisting of specimens loaded under a variable amplitude spectrum and another of an alternative matrix system, subjected to constant amplitude fatigue.
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