Advances in cellular and molecular technologies – in particular, in imaging – have made it possible to understand a vast range of cellular and molecular mechanisms underlying cell function but many more remain obscure.
We describe the combined use of these techniques and the instrumentation required to enable cryo-electron tomography for a vast range of cellular samples.
VCPIP1 interacts with p97, a highly abundant protein implicated in a vast range of cellular activities including the endoplasmic reticulum-associated degradation (ERAD) pathway and HIF1α stability [18].
As2O3 acts on cells through a variety of mechanisms, influencing numerous signal transduction pathways and resulting in a vast range of cellular effects that include apoptosis induction, growth inhibition, promotion or inhibition of differentiation, and angiogenesis inhibition [ 23, 24].
Indeed, there is a vast range of cellular responses to cell matrix interactions, depending on the integrin receptors expressed by the cell and the composition of the surrounding ECM.
AMPK represents a pivotal point in the mTOR pathway regulating a vast range of cellular activities, including transcription, translation, cell size, mRNA turnover, protein stability, ribosomal biogenesis, and cytoskeletal organization [ 37].
The questions over perceived inefficiencies will no doubt continue, but Pilgrim stresses the work of the OAIC is continuing and it was now tending to a vast range of privacy functions.
Halliday and Matthiessen (2013) contend that, while there is a vast range of speech functions in the English language, they concern either giving or demanding commodity.
Nitric oxide (NO) exhibits a vast range of functions in signal transduction and the immune response in mammalian tissues [1].
While rcd1 displays a vast range of well-characterized phenotypes, the function of its closest ortholog, SRO1, is dispensable for normal plant development and stress response [ 1].
Nature employs proteins for a vast range of tasks, and their capacity to evolve to perform diverse functions is one of the marvels of biology.
